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Updated: May 26, 2025

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
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在83个口腔状细胞癌样本中对与miR-31相关的假定基因进行了系统的基因表达分析

Carolin Feldges1, Susanne Jung1, Nikolai Purcz2

  • 1Vascular Biology of Oral Structures (VABOS) Research Unit; Department of Cranio-Maxillofacial Surgery, University Hospital Muenster, Waldeyerstraße 30, Muenster, 48149, Germany.

Head & face medicine
|February 25, 2025
PubMed
概括

研究人员在口腔状细胞癌 (OSCC) 中确定了20个与angiomiR-31相关的基因. 这些发现可能会提高预后可预测性,并指导OSCC患者的新疗法.

关键词:
血管新生的产生.在 MiR3131 里面,你会看到 MiR31 的位置.瘤基因是一种瘤基因.口腔状细胞癌的癌症.目标基因是目标基因.瘤抑制剂 瘤抑制剂

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MicroRNAs01:22

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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