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Updated: May 26, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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lncRNA DUBR是由CTCF调节的,它协调了血液细胞中的染色体格局和基因表达

Hober Nelson Núñez-Martínez1, Gustavo Tapia-Urzúa1, Ángel Josué Cerecedo-Castillo1

  • 1Instituto de Fisiología Celular, Departamento de Genética Molecular, Universidad Nacional Autónoma de México, 04510, Ciudad de México, México.

Nucleic acids research
|February 25, 2025
PubMed
概括

在红细胞发育过程中,CCCCTC结合因子 (CTCF) 约束长非编码RNA DUBR. DUBR调节了造血基因分化基因和染色质的可访问性.

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