长期COVID综合征患者的执行功能缺陷:系统性审查
Siti Maisarah Nasir1, Noorazrul Yahya2, Kah Hui Yap3
1Department of Radiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, 56 000, Malaysia.
Heliyon
|February 25, 2025
概括
长期COVID患者经常经历持续的执行功能 (EF) 缺陷. 这些认知障碍与前脑和小脑区域的大脑变化相关,影响推理和回忆.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 传染性疾病 传染性疾病
背景情况:
- 后COVID-19状态 (长期COVID) 涉及持续症状超过12周感染后.
- 长期的COVID可以显著损害日常生活和生活质量.
- 神经认知缺陷,特别是在执行功能方面,是一个越来越令人担忧的问题.
研究的目的:
- 系统地审查有关长期COVID患者神经认知特征的研究.
- 专门评估长期COVID中的执行功能 (EF) 缺陷.
- 通过神经成像来确定EF缺陷和大脑变化之间的相关性.
主要方法:
- 在PubMed/MEDLINE和Web of Science的系统文献搜索.
- 遵守PICOS和PRISMA 2020指南的要求.
- 使用纽卡斯尔-太华尺度 (NOS) 进行质量评估.
主要成果:
- 从3268个初始记录中,包括了31篇文章.
- 很大一部分长期COVID患者表现出EF缺陷.
- EF 缺陷与影响推理,语言和记忆的额头和小脑区域障碍相关.
结论:
- 评估EF缺陷对于长期COVID患者护理至关重要.
- 了解这些缺陷可以为未来的治疗策略提供信息.
- 这项研究强调了认知障碍和长期COVID中大脑变化之间的联系.
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