开发和验证伊利奥囊综合征痛苦指数的发展和验证
Paul Cavallaro1, Kinga S Olortegui2, Randolph Steinhagen3
1Division of Colon and Rectal Surgery, University of South Florida/Tampa General Hospital, Tampa, FL, USA.
开发了一种新的Ileoanal Pouch综合征痛苦指数,以测量手术后与肠道症状相关的患者痛苦和生活质量. 这种经过验证的工具有助于对复杂的胃肠道患者进行个性化管理.
科学领域:
- 胃肠病学 胃肠病学
- 外科手术的结果
- 患者报告的结果.
背景情况:
- 现有的袋子严重性评分不评估患者的适应性或与肠道功能相关的时间上的痛苦.
- 之前的德尔菲共识确定了囊手术患者的关键症状和后果.
研究的目的:
- 设计和验证基于问卷的评分系统,以测量与肠功能症状相关的痛苦和生活质量.
- 评估患者适应袋子功能和随着时间的推移感知到的痛苦.
主要方法:
- 从IBD中心和倡导网站招募了囊患者.
- 使用问卷评估症状频率,烦和生活质量.
- 创建了Ileoanal Pouch综合征痛苦指数,并评估了其有效性 (测试-重新测试,收,临床).
主要成果:
- 16项困境指数范围从0到64,较高的分数表明更烦人的症状.
- 增加的痛苦指数得分与报告生活质量差的患者比例更高相关.
- 痛苦得分显示出生活质量差的强有力的预测价值 (AUC 0.871) 并与临床测量有很好的相关性.
结论:
- 伊利奥囊综合征困扰指数是一种经过验证的工具,用于以患者为中心地管理伊利奥囊功能.
- 这一指数与严重性评分沿线使用,可在复杂的胃肠道患者中微妙优化肠功能.
- 它解释了随着时间的推移症状的适应,改善了患者的护理和结果.
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