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Updated: May 26, 2025

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
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对旋转手套疾病的原体注射:系统性审查

Rocco Aicale1, Eugenio Savarese1, Rosita Mottola2

  • 1Department of Orthopaedic and Trauma Surgery, Casa di Cura di Bernardini, 74121 Taranto, Italy.

Clinics and practice
|February 25, 2025
PubMed
概括
此摘要是机器生成的。

原体注射对治疗旋转手套疾病 (RCD) 有希望,改善疼痛和功能. 需要进一步进行高质量的研究,以确认这些常见的肩部损伤的最佳方案.

关键词:
原蛋白是一种原蛋白.原体注射 原体注射旋转器袖子的旋转器袖子旋转器袖子部分厚度撕裂的撕裂旋转手套肌病变 旋转手套肌病变 旋转手套肌病变脊上肌病变 - 脊上肌病变

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科学领域:

  • 整形外科 整形外科 整形外科
  • 再生医学是一种再生医学.
  • 运动医学 运动医学

背景情况:

  • 旋转手套疾病 (RCD) 很普遍,影响5-39%的普通人口,超过30%的60岁以上的人.
  • 旋转的复杂解剖学和功能使其易受严重的疾病.

研究的目的:

  • 系统地审查原体注射治疗旋转手套疾病 (RCD) 的疗效.

主要方法:

  • 在主要的科学数据库 (PubMed,Scopus,Web of Science) 进行了系统的文献搜索,直到2024年11月.
  • 研究选择和质量评估由两位独立审查员使用PRISMA指南和修改后的科尔曼方法评分 (CMS) 进行.

主要成果:

  • 包含了8项研究,通常显示出相当好的方法质量.
  • 所有包括的研究都报告了在RCD注射原蛋白后,疼痛和功能有临床相关的改善.
  • 研究中的显著异质性阻止了关于最佳原蛋白类型或注射方案的最终结论.

结论:

  • 原蛋白的使用在减少疼痛,增强功能和改善RCD的肌结构方面似乎是有效的,特别是在部分撕裂和肌病中.
  • 需要高质量的前性研究和长期跟进,以验证这些发现并建立最佳实践.