对与抑郁症或焦虑症相关的初级甲状腺功能障碍症的分析
Ana-Maria Gheorghe1, Claudiu Nistor2,3, Aurelian-Emil Ranetti4,5
1PhD Doctoral School of "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Diseases (Basel, Switzerland)
|February 25, 2025
概括
原发性偏甲状腺症 (PHPT) 与高抑郁和焦虑率 (D/A) 有关. 副甲状腺手术显著改善了D / A症状,突出了超越传统管理的综合患者护理的需要.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 医学审查 医学审查
背景情况:
- 非经典的神经精神疾病表现是公认的原发性偏甲状腺症 (PHPT) 的症状.
- PHPT与抑郁症和焦虑症 (D/A) 等疾病之间的联系是有争议的,但对于患者的福祉来说是重要的.
- 仅仅这些症状并不是典型的暗示甲状腺切除术.
研究的目的:
- 审查最近关于D/A和PHPT之间的关联的发现.
- 评估副甲状腺手术对PHPT患者的D/A结果的影响.
主要方法:
- 2020年1月至2024年10月期间发表的英语原始研究的综合审查.
- 来自16项涉及超过1万名PHPT患者和广泛的高血症队伍的研究数据的分析.
- 包括使用各种D/A诊断工具的研究,包括ICD-10代码和验证的问卷.
主要成果:
- 在PHPT患者中观察到高患抑郁症 (20-65.7%) 和焦虑症 (10.4-38.6%).
- 副甲状腺切除术在改善D/A得分,患病率和严重程度方面显示出好处.
- D/A和血清水平之间没有相关性,但PTH和抑郁症之间存在轻微的正相关性.
结论:
- PHPT管理需要采用整体方法,在传统内分泌护理之外,还应对D/A.
- 副甲状腺手术有助于改善PHPT患者的D/A症状.
- 需要进一步的研究来阐明致病机制,并在PHPT中标准化D/A查.
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