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百岁老人的心脏结构和功能的回声心脏学评估:一个系统的审查
Andrea Sonaglioni1, Gian Luigi Nicolosi2, Giovanna Elsa Ute Muti-Schünemann3
1Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy.
Geriatrics (Basel, Switzerland)
|February 25, 2025
概括
百岁老人表现出心脏变化,如左心室同心重塑和腹功能障碍,增加了心力衰竭的风险与保存的喷射分数 (HFpEF). 建议为这种独特的人群提供个性化的心脏保护治疗.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 对于100岁及以上的个人,心声回声数据有限.
- 之前关于百岁老人的心脏健康的研究使用了小样本大小和多种方法.
研究的目的:
- 系统地审查和总结百岁以上人的心声回声学发现.
- 评估极端年龄对心脏结构和功能的影响.
主要方法:
- 对年龄≥100岁的个体进行的心声回声学研究的系统审查.
- 在没有时间限制的情况下搜索了PubMed,Embase,Scopus和CENTRAL数据库.
- 使用NIH质量评估工具评估偏差风险.
主要成果:
- 分析了8项研究,其中包括1340名百岁老人 (平均年龄为101.4岁).
- 百岁老人表现出左心室同心重塑,扩张性功能障碍 (E/A比率0.8),正常的收缩功能 (LVEF 60.9%) 和轻度至中度的肺高血压 (sPAP 42.1 mmHg).
- 乳静脉缩功能障碍 (LVEF < 50%) 的综合患病率为 15.8%;中度至重度的膜疾病在 < 33% .
结论:
- 百岁老人通常呈现左心室同心重塑和心肌硬度增加,导致腹功能障碍.
- 这些发现使得百岁以上的人容易患上心力衰竭,心力衰竭与保存的喷射分数 (HFpEF).
- 个人心脏保护策略应考虑为百岁老人.
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