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Updated: May 26, 2025

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
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肝酶,一个宿主基因,强烈限制逆转录病毒转录

Brandon Waxman1, Kyle Salka1, Uddhav Timilsina1

  • 1Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA.

mBio
|February 25, 2025
PubMed
概括

肝酶 (HPSE) 通过阻止前病毒转录启动来限制逆转录病毒,独立于其酶活性. 这种新型抗病毒功能向SP1转录因子,具有抑制动物性感染逆转录病毒传播的潜力.

关键词:
主机限制因素的主机限制因素人类免疫缺陷病毒人类免疫缺陷病毒鼠类白血病病毒的病毒现在我们可以看到Provirus.它们是逆转录病毒.转录 转录 是一种转录.

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