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Updated: May 26, 2025

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与治愈艾滋病毒相关的研究:我们现在的状况和未来的发展

Martina Ranzenigo1, Antonella Castagna1,2, Camilla Muccini1

  • 1Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.

The new microbiologica
|February 25, 2025
PubMed
概括

研究人员正在探索基因疗法,LRA,免疫疗法和干细胞移植以治愈艾滋病毒. 虽然取得了显著的进展,但对于广泛获得的艾滋病毒治疗,安全性和可访问性仍然存在挑战.

关键词:
艾滋病毒治愈 治愈艾滋病毒基因治疗的基因疗法免疫疗法 免疫疗法延迟逆转剂是一种延迟逆转剂.干细胞移植 干细胞移植

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Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
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