从直肠神经内分泌瘤的淋巴结转移的复发模式和映射
Ayumi Takaoka1,2, Shunsuke Tsukamoto3, Yasuyuki Takamizawa1
1Department of Colorectal Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-Ku, Tokyo, 104-0045, Japan.
International journal of colorectal disease
|February 25, 2025
概括
直肠神经内分泌瘤 (NETs) 的手术切除显示了淋巴结转移的高率. 然而,全腹膜切除提供了良好的长期预后,即使存在转移.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内分泌学 在内分泌学.
背景情况:
- 直肠神经内分泌瘤 (NETs) 缺乏长期结局数据.
- 手术后淋巴结转移的频率是未知的.
研究的目的:
- 调查长期的临床结果.
- 确定手术切除后直肠NET中淋巴结转移的频率.
主要方法:
- 对51名直肠NET患者进行了全面中直肠切除术 (2000-2020年) 的回顾性分析.
- 排除神经内分泌癌的可能性.
- 淋巴结转移的评估和长期预后.
主要成果:
- 淋巴结转移发生在39.2%的患者中.
- 在7.8%的患者中观察到侧侧淋巴结转移.
- 转移和5年无复发存活率之间没有显著的关联 (p=0.094).
结论:
- 截面NET外科手术与全截面切除有高的淋巴结转移率.
- 手术切除提供了一个良好的预后,尽管淋巴结转移.
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