两个新的内脏肥胖指标与美国成年人心力衰竭之间的关联:一个横截面研究
Xi Luo1, Bin Cai2,3, Weiwei Jin1
1Department of Clinical Nutrition, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Metabolic syndrome and related disorders
|February 25, 2025
概括
心脏代谢指数 (CMI) 和内脏脂肪指数 (VAI) 以及它们的年龄调整版本与心力衰竭 (HF) 风险有关. 与其他指标相比,CMI-age在早期HF识别方面表现出优越的预测能力.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 内脏肥胖是心血管疾病的重要危险因素,包括心力衰竭 (HF).
- 像心脏代谢指数 (CMI) 和内脏脂肪指数 (VAI) 这样的新型人体指数正在被探索,因为它们与代谢功能障碍和心血管风险的关联.
- 这些指数的预测价值,特别是它们的年龄调整形式 (CMI-age,VAI-age),对于早期HF检测需要进一步研究.
研究的目的:
- 调查CMI,CMI年龄,VAI和VAI年龄与心力衰竭 (HF) 患病率之间的关联.
- 为了比较这四个内脏肥胖指标的预测性表现,以识别患高血压风险的个体.
- 为早期HF检测和管理提供潜在生物标志物的洞察力.
主要方法:
- 这是一项横截面研究,利用了2011-2018年国家健康和营养检查调查 (NHANES) 8999名参与者的数据.
- 使用多变量回归分析来评估CMI,CMI年龄,VAI,VAI年龄和高频率之间的关联.
- 用接收机操作特征 (ROC) 曲线分析来评估和比较高频指数的预测准确性.
主要成果:
- 在原始模型和调整模型中,CMI,CMI-age,VAI和VAI-age都与HF风险有显著的正相关性.
- 较高的CMI,CMI年龄,VAI和VAI年龄四分位数与较低的四分位数相比,与HF风险显著增加有关.
- 与CMI (0.610),VAI (0.593) 和VAI-age (0.689) 相比,CMI-age显示了ROC曲线 (0.700) 下的最高面积,这表明HF的预测能力优于CMI (0.610),VAI (0.593) 和VAI-age (0.689).
结论:
- CMI,CMI年龄,VAI和VAI年龄独立地与心力衰竭风险增加有关.
- 对于HF的早期预测,CMI-age显然是一个比CMI,VAI和VAI-age更有效的指标.
- 这些发现强调了CMI-age在临床实践中的潜在实用性,用于识别高风险的HF个体,帮助预防和管理策略.
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