急性黄斑神经网膜病变随着现代的mRNACOVID-19疫苗接种
William B Marcus1, Roger A Goldberg
1Bay Area Retina Associates, Walnut Creek, California .
Retinal cases & brief reports
|February 25, 2025
概括
在mRNACOVID-19疫苗接种后发生了一例急性黄斑神经网膜病变 (AMN),在增强剂接种后恶化. 症状在15个月内自发改善,没有治疗.
科学领域:
- 眼科医生 眼科 眼科
- 疫苗学 疫苗学 疫苗学
- 免疫学 免疫学 免疫学
背景情况:
- 急性黄斑神经联络病 (AMN) 是一种罕见的疾病,影响着黄斑.
- 在全球范围内,mRNA COVID-19 疫苗已被广泛使用.
研究的目的:
- 报告一种与mRNA COVID-19疫苗接种暂时相关的急性黄斑神经网膜病变 (AMN) 病例.
主要方法:
- 病例报告详细介绍了临床表现,诊断成像 (OCT, fundus摄影,自光学) 和多式血管学 (ICG,光素).
主要成果:
- 一名79岁的男子在接种第二剂mRNACOVID-19疫苗后发展了AMN.
- 症状和成像发现在第三剂mRNA疫苗后恶化.
- 自发改善发生在最初呈现后15个月,没有特殊治疗.
结论:
- 助推剂后的时间关系和恶化表明mRNA COVID-19疫苗和AMN之间可能存在因果关系.
- 临床医生可能会考虑在AMN疫苗接种后经历AMN后疫苗接种的患者中使用替代疫苗载体或上述助推剂.
- 这一案例凸显了疫苗接种后监测罕见的眼部副作用的重要性.
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