视网膜中毒性二次到无性 视网膜中毒药C注射
Joseph B Alsberge1, Zakary Hoffelt
1Department of Ophthalmology, Northwest Permanente, Vancouver, Washington.
Retinal cases & brief reports
|February 25, 2025
概括
在玻璃眼外科手术期间,意外注射米托米辛C (MMC) 进入脑下膜空间可能会导致局部视网膜毒性. 这一案例突出显示了下腺体的位置的风险,导致下腺体缩,尽管保持了视力敏度.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜外科手术 视网膜外科手术
- 视光眼管理 视光眼管理
背景情况:
- 线粒素C (MMC) 常用于玻璃眼外科手术,以提高手术结果.
- 亚子注射是提供MMC以调节痕的标准.
- 眼内注射的潜在并发症需要仔细考虑.
研究的目的:
- 为了记录一个视网膜毒性病例,该病例是由于无意中注射了mitomycin C.
- 审查在眼部手术中与米托米辛C注射相关的并发症相关的文献.
- 为了强调精确的注射技术在绿眼外科手术中的重要性.
主要方法:
- 一个病例报告,一名患者在米托米C注射后出现了不良反应.
- 关于米托米辛C诱导的眼睛毒性的现有医学文献的综述.
- 临床检查和成像,以评估视网膜损伤的程度.
主要成果:
- 一名73岁的男性患有局部视网膜,出血和闭塞性血管病变.
- 这种并发症归因于由于膜穿刺而导致的米托米辛C无意中被放置在膜下.
- 一个月后观察到胆管缩,但斑点被遗留,视力敏度保持稳定.
结论:
- 在试图注射TENON下注射时,可能会发生意外的MITOMYCIN C的上下注射.
- 亚视网膜线下菌素C可以导致显著的局部视网膜毒性和胆网膜变化.
- 在注射技术中保持警至关重要,以防止在玻璃眼瘤手术中出现严重的眼部并发症.
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