心脏代谢指数和白尿之间的关联:来自NHANES 2017-2020年的证据
Qiming Xu1,2, Junyan Lin2, Lin Liao1,2
1Institute of Kidney Disease of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
PloS one
|February 25, 2025
概括
心脏代谢指数 (CMI) 与较高的白蛋白尿风险有关,这是损伤的标志物. 这项研究表明,CMI可以帮助评估病风险,并指导早期干预策略.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 代谢健康 代谢健康
背景情况:
- 专尿是损伤和慢性病 (CKD) 风险的关键指标.
- 心脏代谢指数 (CMI) 显示了查功能衰竭的潜力.
- 需要进一步调查CMI和白蛋白尿之间的关联.
研究的目的:
- 为了检查CMI和白尿之间的关系.
- 为临床诊断,评估和病早期干预提供见解.
主要方法:
- 使用NHANES数据 (2017-2020) 的横截面研究.
- 使用Triglyceride/HDL-C比率乘以腰与身高比率 (WHtR) 计算的CMI.
- 采用了多因素逻辑回归和两阶段线性回归模型.
主要成果:
- 3,339名参与者的12.38%患有白色素尿,患病率随着CMI四分位数的增加而增加.
- 较高的CMI与增加的白尿患病率有显著的相关性 (OR = 2.26).
- 观察到CMI和白蛋白尿之间存在非线性关系,折叠点为0.92.2.
结论:
- CMI水平与白尿患病率有显著的相关性.
- CMI可以作为评估病风险的有价值生物标志物.
- 这些发现支持CMI在早期发现和治疗功能衰竭方面的作用.
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