新生儿抗菌剂:从业者决定和诊断确定性
Naomi E Spotswood1,2,3, Erin Grace4,5,6, Peter A Dargaville3,7
1From the Women's, Children's and Adolescents' Health Program, Burnet Institute, Melbourne, Victoria, Australia.
The Pediatric infectious disease journal
|February 25, 2025
概括
新生儿抗菌药物处方是复杂的,受临床因素和不确定性的影响. 提高指导方针的一致性和了解医疗文化影响是更好的管理的关键.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 临床药理学 临床药理学
背景情况:
- 在住院的新生儿中,抗菌剂的使用是常见的.
- 影响处方决策和实践变化的因素尚不清楚.
研究的目的:
- 调查澳大利亚新生儿单位对抗微生物药物处方决定的影响.
- 评估医生对新生儿抗菌素使用的信心和诊断确定性.
主要方法:
- 在3个澳大利亚新生儿病房中对56名医生进行了横截面调查.
- 调查问卷评估了诊断确定性和对68种抗菌药物疗程和11种非处方感染评估的影响.
主要成果:
- 在开始时高度遵守指导方针 (84%).
- 临床因素,症状和实验室的影响有所不同;同事咨询影响了决策.
- 实践者的信心有所不同,特别是在未经证实的感染;团队一致性低 (14-50%).
结论:
- 抗菌素的处方受临床,实验室,从业者,团队和中心特定因素的影响.
- 临床不确定性和指导方针的变化导致实践的变化.
- 未来的管理需要一致的指导方针,更好的诊断辅助工具和了解医疗文化的影响.
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