相关实验视频

Updated: May 26, 2025

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

19.3K

使用Word2Vec和分子模拟发现新的五抑制剂,对抗粉样β聚合

Yin-Lei Han1, Huan-Huan Yin1, Chen Li1

  • 1College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China.

ACS chemical neuroscience
|February 25, 2025
PubMed
概括

研究人员发现了一种新型的五,PALIR,它有效地抑制了阿尔茨海默病 (AD) 中的粉样β聚合. 这种对开发针对有毒粉样蛋白的新疗法充满希望.

关键词:
在Word2Vec中使用.聚合方式 聚合方式 聚合方式粉样化物-β-β 的存在.分子动力学模拟模拟这是一种五类.

更多相关视频

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

11.8K
Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain10:01

Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain

Published on: October 25, 2017

11.1K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.2K