在风险决策过程中Cingulo-Opercular激活的性别差异在外化障碍的年轻人中
Olivia K Murray1, Paola Mattey-Mora1, Joseph Aloi1
1Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA; Adolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Psychiatry research. Neuroimaging
|February 25, 2025
概括
与其他组相比,外部化男性在危险决策过程中表现出更大的右背中前额叶皮层激活. 这突显了外化障碍的年轻人冒险的神经生物学上的性别差异.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 有风险的决策缺陷与不安全的行为有关.
- 决策中的性别差异在患有外化障碍的风险青少年中未得到充分研究.
- 男性的外化病理与风险更高的决策有关,但女性的模式不太了解.
研究的目的:
- 在风险青少年中研究风险决策的神经生物学中的性别差异.
- 识别风险行为的性别特异性脆弱性.
- 在风险评估期间检查大脑激活模式.
主要方法:
- 168名青少年在功能磁共振成像 (fMRI) 过程中完成了气球模拟风险任务.
- 参与者被分为四组:外部化男性,外部化女性,控制男性和控制女性.
- 分析了fMRI数据,以比较决策过程中不同组的脑激活.
主要成果:
- 外向化雄性在右侧中背前额叶皮质/背前带状皮质中表现出更大的激活.
- 这种加剧的激活与风险承担的增加相关,因为气球爆炸的概率上升.
- 与外部化男性相比,在其他组中没有观察到显著差异.
结论:
- 研究结果揭示了年轻人风险决策的神经生物学上的显著性别差异,与心理病理的外部化有关.
- 在认知控制和冲动抑制中,带环-管网络的作用是有意义的.
- 了解这些特定于性别的神经模式对于开发有针对性的干预措施来预防危险行为至关重要.
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