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Updated: May 25, 2025

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing
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烯衍生物作为外膜透剂,通过多目标作用模式对抗MDR阴性细菌

Qionglu Duan1, Min Yuan2, Xican Ma1

  • 1State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.

European journal of medicinal chemistry
|February 25, 2025
PubMed
概括

新的pyrylium衍生物作为抗生素辅助剂,通过破坏它们的外膜来增强对抗多药耐药的格拉姆阴性细菌 (如Acinetobacter baumannii和Escherichia coli) 的治疗.

关键词:
LptA/LptC的相互作用在MDR中,有格拉姆阴性细菌.外膜透剂的外膜透剂是什么?烯衍生物的衍生物有协同效应的效应.

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