精确的寡聚阻断CCDC25 与中性细胞外细胞陷中的DNA相互作用 抑制瘤转移

Chenxu Zhu1, Chuang Li1, Yibo Du1

  • 1School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.

PubMed
概括

奥利戈阿吉尼尼R5,R7和R9通过阻断瘤细胞和中性粒细胞细胞外陷 (NET) 之间的相互作用,有效地抑制癌症转移. 这些化合物具有较低的毒性,并减少转移到肝脏和肺部等遥远器官的转移.

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