相关实验视频

Updated: May 5, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

几个卵泡的卵细胞检索不需要止痛:一个大规模的多中心疼痛分析

Isotta M Magaton¹, Martina Nordin², Ikbale Siercks³

¹Division of Gynaecological Endocrinology and Reproductive Medicine, University Women`s Hospital, Inselspital, Friedbühlstrasse 19, 3010 Bern, Switzerland..

Reproductive biomedicine online

|February 25, 2025

概括

没有麻醉的卵细胞检索 (OCR) 对于卵泡很少的女性来说通常是温和的. 这种程序可以在没有止痛药的情况下进行,从而节省了试管婴儿治疗的时间和成本.

科学领域:

生殖医学生殖医学
在体外受精 (IVF)

背景情况:

卵细胞检索 (OCR) 是试管婴儿的一个关键步骤.
对于OCR的麻醉和镇痛的必要性,特别是在毛囊较少的女性中,受到争论.
尽量减少程序负担和成本是辅助生殖技术的一个关键考虑因素.

研究的目的:

为了评估卵细胞检索 (OCR) 的疼痛强度,无需麻醉和止痛.
评估获取卵细胞数量与疼痛水平之间的关系.
在特定的患者群体中确定在没有麻醉的情况下进行OCR的可行性.

主要方法:

在德国和瑞士的七个试管婴儿中心进行了一项多中心观察研究.
分析了2022年1月至2023年3月期间2290次自然或最小刺激试管婴儿周期 (1039名患者) 的数据.
疼痛评分使用视觉模拟量表 (VAS,0-10),统计分析使用线性混合模型进行评估.

主要成果:

在OCR期间疼痛的中位数分数为3.0 (轻度疼痛).
疼痛评分显示轻微,临床上无意义的增加,获得的卵细胞数量较高 (0-1个卵细胞: 3.0; 2-5个卵细胞: 3.42; ≥6个卵细胞: 4.14).
随着重复的试管婴儿周期,疼痛强度略有下降,需要住院治疗的并发症率为<0.1%.

结论:

没有麻醉和镇痛的卵细胞检索 (OCR) 会导致低到中等卵泡数量的女性的轻度疼痛强度.
在没有麻醉和止痛的情况下,可以安全地提供OCR,从而可能减少手术时间和成本.
这些发现支持在选定的试管婴儿患者群体中简化OCR协议.

关键词:

麻醉麻醉是一种麻醉.吸入针的使用方法复杂性复杂性复杂性自然的自然IVF试管婴儿卵细胞检索卵细胞检索疼痛疼痛疼痛疼痛

更多相关视频

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

Gene Expression Analyses in Human Follicles

Gene Expression Analyses in Human Follicles

Published on: February 17, 2023

相关概念视频

Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

Analgesia and Pain Management

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...