慢性病相关的和以患者为中心的结果:系统性审查
Teng Wang1, Jing Xin Goh1, Shrey Seth1
1Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2006, Australia.
Journal of nephrology
|February 25, 2025
概括
慢性病相关的 (CKD-aP) 严重影响生活质量. 有效的管理是至关重要的,但对于预透析和腹膜透析患者需要更多的研究.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
背景情况:
- 慢性病相关的 (CKD-aP) 是影响患者福祉的显著和衰弱的症状.
- CKD-aP对受影响个体的日常活动和整体生活质量产生负面影响.
研究的目的:
- 系统地审查和综合有关CKD相关的和以患者为中心的结果之间的关系的现有证据.
- 确定受CKD-aP影响的关键以患者为中心的结果,并评估证据的强度.
主要方法:
- 从2000年到2024年6月,在主要数据库 (PubMed,Medline,Embase,CINAHL,Web of Science) 进行了全面的文献搜索.
- 质量评估和数据提取使用标准化的Joanna Briggs Institute (JBI) 工具和修改后的提取表格进行.
主要成果:
- 该审查包括29项研究,涉及147174名接受血液透析 (HD) 和腹腔透析 (PD) 的患者.
- 受影响的关键结果包括生活质量 (21项研究),睡眠质量 (17项研究),焦虑/抑郁 (11项研究) 和死亡率 (7项研究).
- 严重的CKD-aP与增加的药物使用,减少HD遵守性和更高的住院率相关;对预透析和PD患者的数据有限.
结论:
- 与CKD相关的会对患者的治疗结果产生重大负面影响,强调需要有效的管理策略.
- 对于预透析,保守和PD患者群体来说,进一步的研究是必不可少的,以充分理解和解决CKD-aP的影响.
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