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在自身免疫性多胞胎症候群病 (Candidiasis Ectodermal dystrophy) 中的脏疾病 (APECED):一个系统性审查

Mohammadreza Shafiei¹, Solale Hosseini², Soodeh Ghadimi³

¹Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran. Mohammadrezashafiei.md@gmail.com.

|February 25, 2025

概括

自身免疫性多性腺瘤症候群性外皮缩症 (APECED) 患者经常出现脏问题,脏瘤是最常见的. 早期监测脏并发症对于APECED患者的更好的结果至关重要.

科学领域:

免疫学免疫学免疫学
腎臟病學 (nephrology) 是一種醫學專業.
遗传学遗传学是一个

背景情况:

自体免疫多分泌症候群症外皮变 (APECED) 或自体免疫多分泌症综合征I型 (APS-I) 是一种免疫的先天错误.
它表现为免疫失调,内分泌问题和非内分泌表现,如慢性粘膜皮肤候群病.
脏疾病是APECED患者显著的,研究不足的并发症.

研究的目的:

系统地审查APECED患者并发症的文献.
为了确定与APECED相关的脏疾病的患病率和类型.
强调脏监测在APECED管理中的重要性.

主要方法:

在PubMed,Web of Science和Scopus进行了全面的文献搜索.
对APECED的临床和免疫学特征进行了系统审查.
选择了包括APECED患者在内的研究,这些患者至少有一种部并发症.

主要成果:

分析了30项研究中的93名APECED患者.
在超过38%的患者中存在瘤瘤.
管间炎 (23%),高血压 (13%),尿路感染 (20.5%) 也是常见的并发症.

结论:

脏并发症是APECED患者的一个重大问题.
定期监测功能对于管理APECED至关重要.
解决脏问题可以改善患者的治疗结果,并保持功能.

关键词:

空气中的空气.在APECED中,您可以使用APECED.自身免疫性多性肌内膜异位症.免疫的天生的错误免疫的天生的错误脏结症是什么脏结症主要免疫缺陷是一个主要的免疫缺陷.

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