睡眠,体力活动和营养的最小和最佳组合变化与所有原因死亡风险相关
Emmanuel Stamatakis1,2, Nicholas A Koemel3,4, Raaj K Biswas3,4
1Mackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. emmnuel.stamatakis@sydney.edu.au.
优化睡眠,体力活动和营养 (SPAN) 一起显著降低死亡风险. 即使是这些行为中的小改进也可以导致所有死因的死亡率大幅减少.
科学领域:
- 生活方式 医学 医疗
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 睡眠,体力活动和营养 (SPAN) 是关键的健康行为,经常被孤立地研究.
- 了解它们对死亡率的综合影响对于全面的健康战略至关重要.
研究的目的:
- 研究睡眠,体力活动和营养与全因死亡率的协同作用.
- 确定所需的最低行为变化,以显著降低死亡风险.
主要方法:
- 一项前性队列研究,对59,078名英国生物库参与者进行了为期7天的可穿戴追踪和饮食评估.
- 机器学习被用来量化睡眠和中度至强度的体力活动 (MVPA).
- 考克斯的比例危险模型分析了SPAN行为和剂量反应变化组合的三分之一的死亡风险.
主要成果:
- 适度睡眠,高MVPA和良好的饮食质量的最佳组合与64%的死亡风险降低有关 (HR:0.36).
- 在SPAN行为 (15分钟的睡眠,1.6分钟的MVPA,5个DQS点) 的小,综合增加与10%的较低死亡风险有关.
- 在SPAN行为显著的综合增加与50%的死亡风险降低相关 (HR:0.50).
结论:
- 睡眠,体力活动和营养的综合修改提供了与死亡率有关的显著健康益处.
- 这些发现支持整体健康建议,强调SPAN行为的协同效应.
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