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结合PDO的分子特征和治疗分析,预测临床反应并指导PDAC个性化治疗

Peng Li1,2,3, Minli Huang1,2, Mengyao Li1,2

  • 1Division of Cancer Biology, Laboratory Animal Center, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, PR China.

Journal of experimental & clinical cancer research : CR
|February 26, 2025
PubMed
概括

患者衍生器官 (PDO) 和异种移植 (PDOX) 准确地模拟胰腺癌,揭示了个性化治疗的基因组多样性. 这些模型显示UGT1A10影响药物反应,有助于向治疗的开发.

关键词:
基因组多样性 基因组多样性免疫治疗是一种免疫疗法.胰腺管道腺癌 (PDAC) 是一种患者衍生器官 (PDO) 的患者衍生器官.个性化治疗 个性化治疗

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