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非小细胞肺癌:真实世界基于人口的队列研究

Alessandra Buja¹, Massimo Rugge², Alberto Bortolami³

¹Department of Cardiologic, Vascular and Thoracic Sciences, and Public Health, University of Padova, Via Loredan, 18, 35100 Padova, Italy.

|February 26, 2025

概括

与2017年相比,2019年非小细胞肺癌 (NSCLC) 患者队列的死亡风险较低,癌症特异性生存率改善. 然而,2019年队列的治疗费用较高,主要是由于药物管理和服务.

科学领域:

在瘤学瘤学.
卫生经济学卫生经济学
流行病学流行病学

背景情况:

对非小细胞肺癌 (NSCLC) 患者的回顾性分析.
使用了威尼托地区癌症登记处2017年和2019年队列的数据.
专注于患者的治疗结果和治疗费用.

研究的目的:

评估2017年和2019年诊断的NSCLC患者临床结果和治疗成本的差异.
评估管理变化对生存和医疗保健支出的影响.
为实践瘤实践提供有关成本效益和患者护理的信息.

主要方法:

两个发生的NSCLC队列的比较 (2017年:493名患者,2019年:557名患者).
诊断后三年随访,以评估结果.
康克斯回归用于生存分析;线性回归用于治疗成本分析.

主要成果:

2019年队列显示整体死亡风险明显降低 (HR 0.84;p=0.024).
2019年队列的第三阶段NSCLC患者的癌症特异性存活率显著提高 (HR 0.61;p=0.015).
2019年队列的整体治疗费用较高 (系数为0.16;p=0.025),主要是药物管理,门诊服务和医疗设备,但宿舍和住院费用较低.

结论:

在2017年和2019年NSCLC队列之间观察到临床结果和患者相关成本的显著差异.
该研究强调了在常规瘤学中持续监测临床结果和管理成本的必要性.
这些发现突出了不断变化的治疗模式及其对NSCLC护理的经济影响.

关键词:

在NSCLCLC中,我们可以看到.医疗保健成本医疗保健成本卫生经济学卫生经济学肺癌是一种肺癌.基于人口的研究.现实世界的瘤学.

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