双坑网络:一个案例报告和文献综述
Mitsuru Nishiyama1,2, Noriaki Fukuhara3, Hiroshi Nishioka3
1Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, 1-185, Kohasu, Oko-cho, Nankoku City 783-8505, Kochi, Japan.
Cancers
|February 26, 2025
概括
双 pituitary神经内分泌瘤 (PitNETs) 是罕见的,经常呈现激素过量,如壮症或库辛氏病. 这些瘤可能以一个或两个不同的质量出现,需要仔细诊断.
科学领域:
- 内分泌学 在内分泌学.
- 神经瘤学神经瘤学
- 病理学 病理学 病理学
背景情况:
- 双 pituitary神经内分泌瘤 (PitNETs) 涉及 pituitary 腺体内的两个不同的瘤,这是一个罕见的临床现象.
- 这些瘤在成像上可能呈现为单独的质量,或者只有在病理学检查后才能被确定为两个独立实体.
- 由于其复杂的临床,放射和病理形状,了解双PITNET的特征至关重要.
研究的目的:
- 分析大量的双PitNET病例队列,以阐明其临床,病理和放射性特征.
- 为了确定与双PitNETs相关的最常见的临床表现和激素过量.
- 描述涉及双PitNETs的主要瘤细胞类型和转录因子系.
主要方法:
- 进行了一项全面的文献审查,分析了142例双PitNET的数据.
- 临床特征,病理发现 (包括瘤细胞类型和转录因子) 和放射学数据被提取和分析.
- 进行了统计分析,以确定不同临床综合征的患病率和瘤特征.
主要成果:
- 巨 (45.5%) 是最常见的临床表现,其次是库辛病 (35.1%) 和益生菌瘤 (17.9%).
- 病理学分析显示,体型 (28.9%) 和皮质型 (26.8%) 瘤占主导地位,性腺型瘤的比例不断上升.
- 放射学发现显示,双 (45.1%) 与单个 (47.6%) 瘤呈现的发病率几乎相同,突出显示了错过微型瘤的潜力.
结论:
- 双坑NET通常是由于至少一个功能性瘤的荷尔蒙过量而被诊断出来的.
- 呈现方式可能具有误导性,其中很大一部分呈现为单一的病变,需要对共存的微小病变保持警.
- 诊断和治疗策略的进步正在改善这些复杂的垂体瘤的管理.
相关概念视频
Case Studies
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
Methods of Documentation III: PIE
Problem-intervention-evaluation (PIE) is a systematic approach to documentation used in healthcare settings for clinical decision-making and patient care planning. It is a structured approach to organizing patient data based on problems, interventions, and evaluations. Here's a breakdown of its key features and considerations:
Methods of Documentation VI: Case Management Model
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic illness...
For example, a patient with a chronic illness...
Introduction to Epidemiology
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...


