过早出生和SARS-CoV-2:是否存在相关性?
Federica Perelli1,2, Annalisa Vidiri3, Giovanna Palomba4
1Pediatric Gynecology Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Biomedicines
|February 26, 2025
概括
感染SARS-CoV-2 (COVID-19) 的孕妇面临更高的早产风险. 预防和监测对于改善母亲和胎儿的结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行引起了人们对其对怀孕的影响的担忧.
- 了解SARS-CoV-2对怀孕结果,特别是早产的影响至关重要.
研究的目的:
- 审查和总结有关SARS-CoV-2感染与孕妇早产之间的联系的现有数据.
- 为了评估COVID-19阳性孕妇早产风险.
主要方法:
- 从2020年3月到2023年12月进行的系统文献搜索.
- 搜索的数据库包括PubMed和Web of Science,遵循PRISMA指南.
- 包括那些将母亲COVID-19感染与早产结果相关联的研究.
主要成果:
- 对13项研究的分析显示,在SARS-CoV-2-阳性孕妇中,早产的发病率更高.
- 感染妇女的平均早产发病率为18.5%,而非感染的对照组为10%.
- 第三个三个月的感染与早产的最高风险有关.
结论:
- 怀孕期间的SARS-CoV-2感染与早产和剖腹产的风险增加有关.
- 症状严重程度和并发症加剧了不良产科结果的风险.
- 预防SARS-CoV-2感染和对孕妇进行密切监测对于降低早产率至关重要.
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