深度学习在眼的检测和进展预测:一个系统的审查和元分析
Xiao Chun Ling1,2,3, Henry Shen-Lih Chen1, Po-Han Yeh4
1Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan 333, Taiwan.
Biomedicines
|February 26, 2025
概括
深度学习 (DL) 卓越于使用 fundus 摄影和 OCT 成像来诊断青光眼. 未来的DL模型需要多模式数据来更好地预测青光眼的进展.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 人工智能的人工智能
背景情况:
- 青光眼的诊断和进展预测对于预防视力丧失至关重要.
- 深度学习 (DL) 在分析医疗图像进行各种诊断任务方面表现有前途.
研究的目的:
- 系统地评估DL算法的诊断和预后性能,以检测和预测青光眼的进展.
- 用 fundus 摄影和光学连贯性断层扫描 (OCT) 成像来评估 DL 的性能.
主要方法:
- 在主要数据库中进行了全面的文献搜索,截至2024年10月.
- 使用双变随机效应模型进行了元分析,以汇集性能指标.
- 关键指标包括聚合的灵敏度,特异性,概率比率和AUROC.
主要成果:
- DL通过 fundus 摄影 (AUROC 0.90) 和 OCT (AUROC 0.86) 显示了高准确度的青光眼诊断.
- 与诊断任务相比,DL在预测青光眼进展方面的表现不那么强大.
- 内部验证数据集的准确性高于外部数据集.
结论:
- DL算法在使用 fundus 摄影和 OCT 进行青光眼诊断时非常有效.
- 整合多式联络数据和广泛的现实世界验证对于改善基于DL的青光眼进展预测至关重要.
相关概念视频
Glaucoma: Overview
494
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
494
Open Angle Glaucoma: Treatment
384
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
384
Angle Closure Glaucoma: Treatment
426
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
426


