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Updated: May 25, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
09:38

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针对EGFR突变肺癌的瘤微环境:机遇和挑战

Jeong Uk Lim1, Junyang Jung2, Yeon Wook Kim3

  • 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Biomedicines
|February 26, 2025
PubMed
概括

氨酸激酶抑制剂 (TKI) 对EGFR突变肺癌具有前景,但耐药性是一个问题. 瘤微环境 (TME) 在TKI耐药性中发挥着关键作用,提供了新的治疗点.

关键词:
生物标志物生物标志物皮肤生长因子受体突变肺癌是一种肺癌.电阻的阻力可以瘤微环境是一个微环境.

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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib09:38

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