儿科息护理中的多药学:探索医生和药剂师之间的差异
Daniele Mengato1, Anna Zanin2, Fernando Baratiri2
1Hospital Pharmacy Department, Azienda Ospedale-Università Padova, Via Giustiniani, 35128 Padua, Italy.
Children (Basel, Switzerland)
|February 26, 2025
概括
非标签药物处方在儿科息治疗 (PPC) 中很常见,医生和药剂师的看法之间存在重大差异. 标准化的协议和协作对于安全有效的儿科药物使用至关重要.
科学领域:
- 儿科药理学 儿科药理学
- 抚慰性护理医学 抚慰性护理医学
- 药物使用研究 药物利用研究
背景情况:
- 非标签药物使用在儿科息护理 (PPC) 中很常见,原因是儿科特定数据和配方有限.
- 对非标签处方的各种专业看法使实践复杂化,需要加强合作.
- 解决这些挑战对于优化儿童治疗结果至关重要.
研究的目的:
- 调查儿童息护理环境中非标签药物处方的患病率和特征.
- 为了比较医生和临床药剂师对非标签处方的观点.
- 为了确定在这个弱势群体中导致非标签药物使用的因素.
主要方法:
- 一项横截面观察性研究分析了PPC中心169名患者的993份药物处方.
- 非标签处方被医生和药剂师独立评估,差异通过共识解决.
- 统计分析包括奇平方和t测试,以比较专业感知并确定处方特征.
主要成果:
- 药剂师发现非标签使用的比例高 (32.9%) 比医生 (18.4%;p < 0.05).
- 共识确定了26.5%的处方是非标签的,主要是由于说明 (67.9%),剂量 (49.6%) 和年龄 (44.4%).
- 专业评估中的差异凸显了对非标签标准的不同解释.
结论:
- 在儿科息治疗中,非标签处方的普遍性很高,这凸显了对标准化方案的需求.
- 加强医疗保健提供者之间的跨学科合作和沟通对于安全有效的药物使用至关重要.
- 建议制定注册表,进行临床试验,并调整监管框架,以提高儿科药物安全性.
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