儿童肺炎肠道病的危险因素和结果
Noha Heikal1, Alessandra Mari1,2, Jutta Köglmeier1
1Department of Paediatric Gastroenterology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Children (Basel, Switzerland)
|February 26, 2025
概括
儿童的肺炎肠道病很少见,但通常是可以控制的. 然而,某些实验室值,如低血小板和高CRP,肌素和尿素,可能表明结果不佳.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 新生儿科学 新生儿科学
- 儿科手术 儿科手术
背景情况:
- 肺炎肠道病 (PI) 是儿科患者的一种不常见的疾病.
- 儿童PI的潜在原因和风险因素尚不清楚.
研究的目的:
- 调查与儿童肺炎肠道病相关的危险因素.
- 评估被诊断患有PI的儿科患者的结果和预后.
主要方法:
- 从1991年到2021年,对具有PI放射性证据的儿科患者 (>1个月) 的回顾性分析.
- 定义的糟糕的结果是,在PI诊断后一个月内失去肠道自主性或死亡.
主要成果:
- 包括31名儿童 (平均年龄为5岁);常见的基本诊断包括脑和急性淋巴细胞白血病 (ALL).
- 12/31 (38.7%) 在骨髓移植 (BMT) 后发展PI.
- 糟糕的结果 (6/31) 与血小板数量降低,CRP升高,肌素和尿素水平有关.
结论:
- 儿童肺炎肠道病通常有良好的预后,但会带来患病和死亡的风险.
- 较低的血小板计数和升高的CRP,肌素和尿素可能是儿科PI中预后更差的指标.
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