预测性心室异常在患有异常性心室外血栓儿童的预测者
Rita Kunigeliene1,2, Odeta Kinciniene1,2, Germanas Marinskis2,3
1Clinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Universiteto St. 3, 01513 Vilnius, Lithuania.
Children (Basel, Switzerland)
|February 26, 2025
概括
儿童的心室外血栓往往是偶然的,但可以表明潜在的心脏问题. 这些外结的更高频率与儿科患者的腹腔功能障碍有很强的联系.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心脏电生理学 心脏电生理学
- 节律失常学 节律失常学
背景情况:
- 腹腔外血栓在儿童和青少年中很常见.
- 虽然它们往往是良性的,但它们可以表明严重的心脏疾病,如心肌病或通道病.
- 腹腔外吸管与儿童腹腔异常之间的联系需要进一步研究.
研究的目的:
- 为了确定诊断为心室外血栓的儿童心室异常的患病率.
- 调查心室外血栓的负担与心脏结构/功能变化之间的关联.
主要方法:
- 3-18岁的儿科门诊患者的回顾性队列研究,每24小时>5%的外.
- 排除先前诊断为先天性心脏缺陷,心肌病或通道病的患者.
- 对心电图,心脏成像 (包括MRI) 和心脏遗传检测结果的审查.
主要成果:
- 包括131名患者;79.4%的腹腔外血栓被发现是偶然的.
- 心脏核磁共振扫描显示,在三分之一的被扫描患者中,心室功能障碍和心肌纤维化.
- 较高的心室外结频率 (中位数为26.5%/24h) 与心室功能障碍有关.
结论:
- 腹腔功能障碍与儿童腹腔外的较高负担密切相关.
- 这一发现凸显了评估小儿病患频繁出现外结的腹腔异常的重要性.
- 对具体机制和长期影响的进一步研究是有必要的.
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