在COVID前后时期的儿科肺溢液和肺炎球菌疫苗接种趋势:单中心回顾性研究
Denisa Lavinia Atanasiu1, Maria Mitrica1,2, Luciana Petrescu1
1Emergency Clinical Hospital for Children Brasov, Brasov 500063, Romania.
Children (Basel, Switzerland)
|February 26, 2025
概括
儿科肺溢病例在流行后增加,与免疫债务和病原体变化等因素有关. 需要进一步的研究来了解这些趋势并评估疫苗策略.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 胸腔溢出,在胸腔内积聚的液体,经常伴随着肺炎.
- 观察到儿科肺溢病例的增加令人担忧,特别是在流行病后,可能是由于免疫债务和病原体动态的改变.
研究的目的:
- 分析儿科上流的发病率和临床特征的趋势.
- 为了确定常见的病原体,治疗策略,以及受影响儿童的并发症.
主要方法:
- 在2019年1月至2024年9月期间,对66名儿童进行肺部溢血治疗的回顾性分析.
- 收集的数据包括人口统计,疫苗接种情况,症状,住院细节和治疗结果.
主要成果:
- 平均年龄为5岁,男性占主导地位 (57.5%). 只有40.9%的人完成了疫苗接种计划.
- 在过去的两年中,住院病例增加了 (2023年增加16例,2024年增加15例),其中4月是高峰月份.
- 肺炎性链球菌是最常见的病原体,其次是流感性血球菌和空气性伪菌. 常见的治疗包括 ceftriaxone 和 vancomycin; 34.8% 需要胸腔排水.
结论:
- 儿科多流的增加可能与疫情后病原体行为和宿主免疫力的转变有关.
- 非PCV20菌株的出现和流行的3型血清型感染突显了血清型趋势监测和疫苗计划评估的必要性.
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