儿科埃索诺菲尔食道炎的发病率和特征:中西部国家分析
Jose L Zamora-Sifuentes1, Andrew Rorie1, Sharad Kunnath2
1Division of Allergy & Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Children (Basel, Switzerland)
|February 26, 2025
概括
在内布拉斯加州,从2016年到2022年,性食道炎 (EoE) 的发病率为每10万人中10.84. 在2022年,发病率上升至每10万人的32.45,高加索人不成比例地受到影响.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 儿科健康 儿科健康
背景情况:
- 性食道炎 (EoE) 是一种慢性免疫介导的食道疾病.
- 通过食道功能障碍和在活检上高氨基 (>15/HPF) 的特征.
- 全国范围内的发病率不断增加,但州级数据仍然很少.
研究的目的:
- 为了确定内布拉斯加州EoE的发病率.
- 分析与儿科患者的EoE诊断相关的人口因素.
- 为未来的公共卫生干预建立基线数据.
主要方法:
- 对被诊断患有EoE的儿科患者 (<18岁) 的回顾性审查.
- 使用了内布拉斯加州两个主要的儿科胃肠病学中心的ICD编码.
- 从2016年1月1日至2022年12月31日期间收集的数据.
主要成果:
- 在2016-2022年期间,EoE的平均发病率为10.84 / 100,000居民.
- 在2022年内布拉斯加州的点发病率达到32.45/100,000居民.
- 与其他种族/民族群体相比,高加索人被诊断的可能性是3.7倍,在较长的年龄 (9.7岁) 诊断.
结论:
- 这项研究提供了美国第一个针对EoE的州特异性发病率数据.
- 国家一级的流行病学数据对于有针对性的政策制定和社区干预至关重要.
- 强调需要提高对EED管理的认识和资源配置.
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