在长期COVID中功能能力下降,经过17个月的严重急性疾病后
Fernanda Facioli Dos Reis Borges1, Andrezza Cristina Barbosa Braga2, Bernardo Silva Viana3
1Human Movement Science Graduation Program, Universidade Federal do Amazonas, Manaus 6200, Brazil.
International journal of environmental research and public health
|February 26, 2025
概括
在严重的COVID-19感染后出现持续症状的个体显著减少功能能力,氧气摄入量降低,感染后17个月的生活质量下降. 这突显了长期COVID患者的长期心肺挑战.
科学领域:
- 心肺运动生理学 运动生理学
- 传染病研究 传染病研究
- 长时间COVID研究
背景情况:
- 长期COVID是一个重大的公共卫生挑战,在SARS-CoV-2感染后持续出现症状.
- 了解严重的COVID-19的长期心肺连续症对于患者管理至关重要.
- 有限的数据存在于功能能力和心肺运动测试在长期的长期COVID症状的人.
研究的目的:
- 评估和比较患有严重COVID-19后持续症状的个体的功能能力与对照.
- 评估心肺系统的参数,包括气体交换,呼吸肌肉强度和生活质量.
- 研究长期COVID患者的运动测试结果和感知到的运动之间的关系.
主要方法:
- 一项涉及34名参与者的病例控制研究,分为严重的COVID-19与持续症状和对照组.
- 通过6分钟步行测试 (6MWT) 结合气体分析来评估功能能力.
- 进行了螺旋测量,呼吸肌肉强度测试和生活质量调查问卷.
主要成果:
- 在COVID-19组表现出明显较低的6MWT距离,降低了氧气吸收峰值 (V·O2),并在运动期间改变了心率反应.
- 在6MWT期间,COVID-19组中报告了感知呼吸障碍和疲劳的更高评级.
- 回归分析显示,6MWT的表现与感知到的劳力,V·O2和心率之间存在显著的关联.
结论:
- 在严重的COVID-19之后,患有持续症状的个人在感染后17个月表现出功能能力明显受损.
- 低峰氧气吸收和炼期间心率异常的行为是这个队列的特征发现.
- 功能能力受损和生活质量下降强调了对长期COVID患者有针对性的康复策略的需要.
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