前列腺癌检测率与前列腺活检年份之间的关联
Young Jun Uhm1, Woojin Bang1, Jae Hoon Chung1
1Department of Urology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Republic of Korea.
Life (Basel, Switzerland)
|February 26, 2025
概括
从2008年到2022年,每两年进行一次前列腺活检 (PBx),前列腺癌 (PCa) 检测率显著增加. 这一趋势在 PSA 水平较高的老年患者和ISUP等级较高的组中更为明显.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医学统计 医学统计
背景情况:
- 在韩国,前列腺癌 (PCa) 检测率正在上升.
- 前列腺活检 (PBx) 的年份与PCa检测之间的关系需要进行调查.
研究的目的:
- 确定PBx的一年是否与PCa检测率有关.
- 分析PCa检测率与临床因素之间的相关性.
主要方法:
- 在2008年至2022年 (平年) 期间接受PBx的1628名患者的回顾性审查.
- 主要结果:PCa检测率.
- 二次结果:PCa检测率与PBx年和临床因素的关联.
主要成果:
- 在研究期间,PCa检测率从24.8%显著增加到48.9% (R2 = 0.885,p < 0.001).
- 在前列腺特异性抗原 (PSA) 水平升高的患者和国际泌尿病学学会 (ISUP GG) 较高等级组中,检测率更高.
- 对于ISUP GG 2-3和4-5子组来说,增长趋势显著,但对于ISUP GG 1来说,这一趋势并非如此.
结论:
- 在PBx和PCa检测率的年度之间存在显著的正相关性.
- PCa检测的上升趋势受患者年龄,PSA水平和ISUP GG的影响.
- 进一步的研究可能会探索PCa检测观察到的时间增加的根本原因.
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