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Updated: Jul 9, 2026

Egg Microinjection and Efficient Mating for Genome Editing in the Firebrat Thermobia domestica
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Egg Microinjection and Efficient Mating for Genome Editing in the Firebrat Thermobia domestica

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钻石背中的CRISPR/Cas9基因组编辑:目前的进展,挑战和前景

Muhammad Asad1,2,3,4,5, Yanpeng Chang1,2,3,4,5, Jianying Liao1,2,3,4,5

  • 1State Key Laboratory of Agricultural and Forestry Biosecurity, Institute of Applied Ecology, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

International journal of molecular sciences
|February 26, 2025
PubMed
概括

CRISPR/Cas9基因编辑通过使基因功能分析和遗传控制成为可能,正在彻底改变钻石背害虫害管理. 本综述总结了其进展,应用和战略,以克服可持续害虫控制的挑战.

关键词:
这种植物名为Plutella xylostella.这使得CRISPR/Cas9系统的效率提高.基因驱动器的基因驱动器遗传控制是一种遗传控制.遗传修饰是一种基因改造.在位点导向的突变发生.

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CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...