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Updated: May 25, 2025

Monitoring Cleaved Caspase-3 Activity and Apoptosis of Immortalized Oligodendroglial Cells using Live-cell Imaging and Cleaveable Fluorogenic-dye Substrates Following Potassium-induced Membrane Depola
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SARS-CoV-2-ORF-3a通过K+离子通道调节的线粒体功能障碍调节细胞亡

Muhammad Suhaib Qudus1, Uzair Afaq1, Siyu Liu1

  • 1State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

International journal of molecular sciences
|February 26, 2025
PubMed
概括

严重的COVID-19肺损伤是由SARS-CoV-2ORF-3a蛋白质破坏线粒体功能引起的. 恢复水平可以减轻这种损伤和炎症,建议新的治疗点.

关键词:
线粒体的ATP敏感通道 (MitoKATP)在ORF-3a.这就是SARS-CoV-2病毒.灭症 (apoptosis) 是一种死亡的过程.线粒体功能障碍 线粒体功能障碍

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