相关实验视频

Updated: May 25, 2025

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection
11:32

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection

Published on: December 4, 2010

15.3K

来自Debaryomyces hansenii的mRNA出口因子 Gle1的分子结构

Min Jeong Jang1, Soo Jin Lee1, Jeong Ho Chang1,2,3

  • 1Department of Biology Education, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea.

International journal of molecular sciences
|February 26, 2025
PubMed
概括

研究人员确定了酵母 Gle1 的晶体结构,揭示了它的结构和明显的二次结构. 这为对mRNA出口监管至关重要的Gle1-Dbp5相互作用提供了洞察力.

关键词:
Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5 Dbp5德巴里奥米塞斯汉森尼 (Debaryomyces hansenii) 是一种植物.Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1 Gle1IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6 IP6在mRNA出口方面,mRNA出口是非常重要的.核孔复合体是核孔复合体.

更多相关视频

Method for the Isolation and Identification of mRNAs, microRNAs and Protein Components of Ribonucleoprotein Complexes from Cell Extracts using RIP-Chip13:34

Method for the Isolation and Identification of mRNAs, microRNAs and Protein Components of Ribonucleoprotein Complexes from Cell Extracts using RIP-Chip

Published on: September 29, 2012

27.5K
Visualization of Endoplasmic Reticulum Localized mRNAs in Mammalian Cells10:24

Visualization of Endoplasmic Reticulum Localized mRNAs in Mammalian Cells

Published on: December 17, 2012

14.3K

相关概念视频

Nuclear Export of mRNA02:31

Nuclear Export of mRNA

Before mRNAs are exported to the cytoplasm, it is crucial to check each mRNA for structural and functional integrity. Eukaryotic cells use several different mechanisms, collectively known as mRNA surveillance, to look for irregularities in mRNAs. Irregular or aberrant mRNA are rapidly degraded by various enzymes. If a defective mRNA escapes the surveillance, it would be translated into a protein which would either be non-functional or not function properly. One of the primary irregularities in...
7.5K
Nuclear Export01:42

Nuclear Export

The nucleus restricts several proteins within and allows others to pass. The restricted proteins possess a nuclear retention sequence or NRS, anchoring them to the nuclear lamins and preventing their transport to the cytosol. The non-restricted proteins, after their synthesis, are transported to their site of action, such as the cytosol or other organelles, with the help of nuclear export signals or NES.
NES are of three types- the canonical 10-residue long leucine-rich signal and other...
3.6K
Regulated mRNA Transport02:22

Regulated mRNA Transport

In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing...
6.2K
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
5.9K
RNA Structure01:19

RNA Structure

The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
4.6K
Directing Proteins to the Rough Endoplasmic Reticulum01:34

Directing Proteins to the Rough Endoplasmic Reticulum

The organelle-specific signaling sequences direct proteins synthesized in the cytosol to their final destination like ER, mitochondria, peroxisomes, etc. Some of the proteins directed to ER are then trafficked via vesicles to other organelles within the cell or the extracellular environment through the Golgi complex. For example, the rough ER synthesizes soluble proteins for transportation to the lysosomes or secretion out of the cell. It can also synthesize transmembrane proteins that can...
7.1K