胃亚皮质病变的自然过程和长期结果:系统性审查
Masaya Iwamuro1, Hiroyuki Okada2, Motoyuki Otsuka1
1Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
胃亚皮质病变 (SELs) 的生长缓慢,但像大小和成像特征这样的风险因素需要个性化监测. 密切监测高风险SEL对于及时干预和改善患者结果至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜成像系统的成像
背景情况:
- 胃亚皮质病变 (SEL) 经常在内镜检查期间偶然发现.
- 虽然许多SEL是良性的,但有些,如胃肠道 stromal 瘤,需要干预.
- 关于胃SELs的自然过程和长期结果的数据有限.
研究的目的:
- 系统地审查关于胃SELs进展,生长速度和风险因素的证据.
- 为胃亚皮质病变的临床管理策略提供信息.
- 为优化监控协议提供见解.
主要方法:
- 对2000年1月至2024年11月的研究进行了全面的PubMed搜索.
- 包括关于胃SEL随访和进展的原始研究;不包括非英语文章,评论和病例报告.
- 在选277个初始研究和15个手工识别的研究后,分析了41篇文章.
主要成果:
- 报告的胃SEL生长率各不相同:2.0-8.5% (大型研究) 和5.4-28.4% (较小的研究).
- 增长率的差异归因于患者的选择,随访时间和增长标准.
- 增长的危险因素包括更大的初始尺寸,不规则的边缘,异质的回声模式和特定的瘤位置.
结论:
- 考虑到病变大小,成像和风险因素,对胃SEL的个性化管理至关重要.
- 密切监测高风险病变对于及时干预至关重要.
- 需要标准化生长标准和优化后续方案,以提高临床决策和患者的结果.
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