慢性阻塞性肺病与韩国成年人的低肌肉质量之间的关联
1College of General Education, Kookmin University, Seoul 02707, Republic of Korea.
Journal of clinical medicine
|February 26, 2025
概括
低肌肉质量 (LMS) 与老年人慢性阻塞性肺病 (COPD) 有关. 在这项研究中,限制性肺病 (RPD) 与LMS没有显著的关联.
科学领域:
- 老年学是一门学科.
- 肺部病理学 肺部病理学
- 萨尔科佩尼亚研究研究
背景情况:
- 慢性阻塞性肺病 (COPD) 和限制性肺病 (RPD) 在老年人中很常见.
- 这些情况与炎症,氧化应激和减少体力活动有关,这些因素可以导致低肌肉质量 (LMS).
研究的目的:
- 为了调查COPD,RPD和肉症之间的关联.
- 使用来自韩国国家健康和营养检查调查 (KNHANES) 的数据.
主要方法:
- 对8980名40岁以上的参与者进行了横截面分析 (2008-2011 KNHANES).
- 低肌肉质量 (LMS) 根据亚洲肉症工作组 (AWGS) 的标准 (ASM/身高) 定义.
- 通过螺旋测量检测发现的肺部疾病;逻辑回归调整为混因素.
主要成果:
- 慢性肺炎 (37.3%) 和慢性肺炎 (25.3%) 和正常功能 (25.9%) 的LMS患病率最高.
- 经过调整后,COPD与LMS显著相关 (OR: 1.543,95% CI: 1.246-1.910).
- 在RPD和LMS之间没有发现显著的关联 (OR: 1.225,95%CI: 0.997-1.505).
结论:
- 低肌肉质量 (LMS) 与慢性阻塞性肺病 (COPD) 独立相关.
- 在本研究人群中,限制性肺病 (RPD) 与LMS没有显著关联.
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