与COVID-19相关的视网膜血管封闭:一个系统性审查
Argyrios Tzamalis1, Maria Foti1, Maria Georgiadou1
12nd Department of Ophthalmology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, 564 29 Thessaloniki, Greece.
Journal of clinical medicine
|February 26, 2025
概括
COVID-19感染增加了视网膜血管封闭的风险,包括视网膜静脉封闭 (RVO) 和视网膜动脉封闭 (RAO). 这一系统性审查强调了患者的特征和结果,表明COVID-19在这些血管事件中发挥了重要作用.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 血管医学 血管医学
背景情况:
- COVID-19 (2019年冠状病毒疾病) 和SARS-CoV-2免疫接种已经与视网膜血管闭塞事件有关.
- 了解受影响个体的风险因素和特征对于早期检测和管理至关重要.
- 有关COVID-19相关的视网膜血管封闭现有知识需要系统的总结和评估.
研究的目的:
- 为了确定COVID-19相关的视网膜血管封闭 (RVO和RAO) 患者的基线特征.
- 评估有关COVID-19患者和疫苗接种者的视网膜血管封闭现有知识.
- 提供对这些疾病风险较高的人群的见解.
主要方法:
- 对案例报告和系列的系统审查.
- 在PubMed和Scopus数据库中进行的电子搜索.
- 研究遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要成果:
- 包括34项研究,分析了21名患有COVID-19相关视网膜静脉封闭 (RVO) 的患者和15名视网膜动脉封闭 (RAO) 的患者.
- RVO发生在平均年龄为41.9岁,COVID-19/疫苗接种后平均发病时间为12.3天;RAO发生在平均年龄为56.9岁,平均发病时间为14.9天.
- 71.4%的RVO患者的视敏度有所改善,但只有53.3%的RAO患者的视敏度有所改善.
结论:
- COVID-19似乎对血管封闭的发病有显著的贡献,可能会增加血栓栓塞的风险.
- 准确的病理生理机制将COVID-19与视网膜血管封闭联系起来仍然需要完全阐明.
- 需要进一步的研究来全面了解这种关联及其临床影响.
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