由Trichophyton indotineae引起的皮肤感染:病例系列和系统审查
Aurora De Marco1, Giovanni Liguori1, Claudia Cafarchia2
1Section of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.
Journal of clinical medicine
|February 26, 2025
概括
由Trichophyton indotineae引起的皮肤植物病是由于耐药性导致的日益严重的全球问题. 这项研究回顾了病例,并强调伊特拉科纳作为一种常见的治疗方法,同时强调需要更好的诊断和治疗策略.
科学领域:
- 菌类学 菌类学是指菌类学.
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 由Trichophyton indotineae引起的皮肤植物病是一种全球传播的真菌感染.
- 在T. indotineae中出现的药物耐药性带来了重大治疗挑战.
研究的目的:
- 报告四个T. indotineae皮肤植物病例.
- 对T. indotineae病例报告进行系统审查.
- 确定T. indotineae感染的临床,人口和治疗模式.
主要方法:
- 在PubMed的系统文献搜索到2024年12月6日,遵守PRISMA指南.
- 包括英语病例报告/人类T. indotineae感染的系列,通过内部转录间距测序证实.
- 分析了30篇精选的文章,包括64名患者,以及四个新的病例报告.
主要成果:
- 大多数患者 (65.52%) 身体健康或免疫能力强,感染通常呈现为多个身体部位的长期病变,特别是下肢.
- 伊特拉可纳成为最常见的最终治疗方法,在报告的三例病例中实现了完全缓解.
- 患者主要来自亚洲大陆,报告的病例来自南亚.
结论:
- 应怀疑T. indotineae感染导致广泛或反复性皮肤植物病,特别是在有往亚洲旅行史的人群中.
- 迫切需要先进的诊断工具来快速识别T. indotineae及其耐药菌株.
- 为了确定T. indotineae感染的最佳预防措施和治疗策略,需要进行进一步的研究.
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