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肥胖危急病患者的营养治疗:一项观察性研究
Juan Carlos Lopez-Delgado1, Laura Sanchez-Ales2, Jose Luis Flordelis-Lasierra3,4
1Area de Vigilancia Intensiva, Clinical Institute of Internal Medicine & Dermatology (ICMiD), Hospital Clínic de Barcelona, C/Villarroel, 170, 08036 Barcelona, Spain.
患有肥胖症的重症患者往往获得不足的能量和蛋白质,影响死亡率. 优化营养支持对于改善这一群体的结果至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 营养科学 营养科学
- 肥胖医学 肥胖医学
背景情况:
- 肥胖在重症患者中带来了独特的营养代谢挑战.
- 临床实践指南对重症肥胖患者 (PwO) 的营养提供缺乏明确的共识.
- 了解能量和蛋白质摄入的影响对于普华永道的结果至关重要.
研究的目的:
- 评估能量和蛋白质摄入量对肥胖重症患者的影响.
- 分析与PwO营养供应充足度相关的结果.
- 确定影响PwO接受医学营养治疗的死亡率和存活率的因素.
主要方法:
- 一项多中心前性观察研究,涉及37个中心.
- 包括需要医疗营养治疗 (MNT) 的成年患者,重点是PwO (BMI ≥30Kg·m-2).
- 对人口统计数据,并发症,营养状况,能量和蛋白质输送 (前14天),并发症和结果的分析,根据CPG建议按充分性分类.
主要成果:
- 在525名 (28.6%) 患者中,有150名患者患有肥胖症.
- 充足的能量供应 (≥11 Kcal/Kg/d) 与较低的ICU死亡率 (16.5%与32.6%) 和更长的住院时间有关.
- 在94.6%的PwO中,蛋白质供应经常不足 (<0.8g/Kg/d) 或不足 (0.8-1.2g/Kg/d);供应不足与较低的ICU死亡率相比,与供应不足有关.
- 多变量分析表明,充足的能量和不足的蛋白质供应与更好的生存率有关.
结论:
- 在重症监护室住院期间,患有肥胖症的重症患者经常经历不足的能量和蛋白质供应.
- 在PwO中,低于最佳的医学营养治疗可能会显著影响短期死亡率.
- 制定优化MNT输送的策略对于改善肥胖重症患者的治疗结果至关重要.
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