绿色提取的富含抗氧化剂的黄类从树使用深度阳性溶剂
Jafar Khan1, Sajjad Asaf2, Lubna2
1Key Laboratory of Forest Plant Ecology, Northeast Forestry University, Harbin 150040, China.
Molecules (Basel, Switzerland)
|February 26, 2025
概括
这项研究优化了从Fagonia cretica中提取黄类的深度环氧溶剂 (DES),实现了高产量和卓越的抗氧化活性. 绿色化学方法证明了DES可回收性和生物活性化合物回收的成本效益.
科学领域:
- 绿色化学 绿色化学
- 自然产品提取 提取自然产品
- 植物化学 植物化学
背景情况:
- 黄酸是具有显著健康益处的生物活性化合物.
- 有效和可持续的提取方法对于隔离黄类药物至关重要.
- 深度乙溶剂 (DESs) 为传统提取溶剂提供了一个有前途的替代品.
研究的目的:
- 使用DESs优化从Fagonia cretica中提取黄类的提取.
- 为了评估提取的黄素的抗氧化特性.
- 评估DES提取过程的可回收性和可持续性.
主要方法:
- 对六种不同的DES进行选,其中贝他因-酸的效率最高.
- 提取参数的优化:摩尔比率,含水量,固体/液体比率,温度和时间.
- 使用DPPH和基清除试验进行抗氧化活性评估.
- 评估使用活性炭回收的DES可回收性.
主要成果:
- 使用贝他因-酸DES在1:4摩尔比率,25%含水量,1:60g/mL固体/液体比率,50°C和30分钟实现最佳提取.
- 与乙醇提取的相比,DES提取的黄类药物显示出增强的抗氧化活性.
- DES回收效率达到了89.78%,在六个循环后保留了92%的提取效率.
结论:
- 基于DES的提取是一种高效,环保和经济高效的方法,用于分离生物活性黄.
- 优化的方法增强了抗氧化特性,并为绿色化学提供了可持续的替代方案.
- 通过DES提取的Fagonia cretica黄素显示出在营养品和药品中应用的巨大潜力.
相关概念视频
00:56Extraction: Advanced Methods
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is formed in...
01:27Microbial Leaching
Microbial leaching, also known as bioleaching, is an environmentally favorable method for extracting metals from low-grade ores using specific microorganisms. This biotechnological approach is particularly valuable for mining operations targeting copper, gold, and uranium, where traditional extraction methods may be economically or environmentally impractical.Copper Leaching and Microbial CatalysisIn copper bioleaching, crushed ore is arranged into heaps and irrigated with a dilute sulfuric...