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Updated: May 25, 2025

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通过腺病毒对IRE1α-XBP1信号的动态调节

Yumi Jang1,2, Fred Bunz1

  • 1Department of Radiation Oncology and Molecular Radiation Sciences, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Pathogens (Basel, Switzerland)
|February 26, 2025
PubMed
概括

腺病毒血清型5 (HAdV5) 通过激活IRE1α,但阻止XBP1s的产生来操纵未折叠蛋白反应 (UPR). 这种病毒策略逃避宿主防御,突出了感染期间复杂的UPR控制.

关键词:
一个XBP1拼接.腺病毒的病毒.在 p53 里,p53 是一个 p53 的类型.不折叠的蛋白质反应反应

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