相关实验视频

Updated: May 25, 2025

Pooled CRISPR-Based Genetic Screens in Mammalian Cells
00:09

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Published on: September 4, 2019

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个体化聚合的CRISPR/Cas9查确定了CDK2在犬乳腺癌患者中是一种可用药物的脆弱性

Marine Inglebert1,2, Martina Dettwiler1,3, Chang He1,2

  • 1Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.

Veterinary sciences
|February 26, 2025
PubMed
概括

这项研究引入了一种新的方法,使用配对的犬类器官来识别癌症特异性的脆弱性. 研究人员发现,用PF3600向CDK2可能是对犬乳腺瘤的有希望的策略.

关键词:
这种基因是药物可变的基因.显基因组是一个表观基因组.基因编辑工具是基因编辑工具.乳腺瘤是一种乳腺瘤.患者衍生有机物 (PDO) 患者衍生有机物 (PDO)精准医学是一门精准医学.

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Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter06:59

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter

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相关概念视频

M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
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