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Updated: May 25, 2025

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
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鼻内人类重组神经生长因子增强严重创伤性脑损伤儿童的运动和认知功能恢复

Lorenzo Di Sarno1, Lavinia Capossela1, Serena Ferretti1

  • 1Institute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.

Pharmaceuticals (Basel, Switzerland)
|February 26, 2025
PubMed
概括

鼻内神经生长因子 (NGF) 在儿童创伤性脑损伤 (TBI) 恢复方面表现有前途. 一个患有严重TBI的年轻男孩在接受人体重组NGF (hr-NGF) 内鼻治疗后经历了显著的运动和认知改善.

关键词:
脑损伤是因为脑损伤.孩子们的孩子们的孩子们的孩子们.认知功能 认知功能扩散性轴突损伤是指扩散性轴突损伤.鼻内注射 鼻内注射 鼻内注射神经生长因子的神经生长因子

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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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