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Updated: May 25, 2025

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改善药物相互作用的工作模型:对临床前和临床药物开发的影响

James Nguyen1,2, David Joseph1, Xin Chen1,3

  • 1Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, USA.

Pharmaceutics
|February 26, 2025
PubMed
概括

基本的静态模型在药物发现的早期有效排除了药物相互作用的风险. 机械静态模型为需要额外评估的化合物提供进一步评估,改善预测性能.

关键词:
在IVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIVIV药物 药物相互作用排泄的排泄情况

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