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对Temozolomide和Ligustilide对增强脑瘤治疗的纳米粒子联合交付的探索性研究

Gang Ke1,2, Mingxia Zhang1, Pengyi Hu1

  • 1Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China.

Pharmaceutics
|February 26, 2025
PubMed
概括

这项研究开发了结合temozolomide (TMZ) 和Ligustilide (LIG) 的双药纳米粒子,以改善质母细胞瘤 (GBM) 治疗. 这些纳米颗粒增强了药物稳定性,大脑向性和针对GBM的治疗疗效.

关键词:
双重药物载荷的纳米粒子.质母细胞瘤多形连接化物.泰莫索洛米德 (temozolomide) 是一种有毒的药物.

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